"Art work throughout the hotel and galleries is fascinating."
Alice from United States
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"Inside we were free to wander through the multi level museum and enjoy the contemporary artwork at our own pace."
Kleime
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"Unique property with two-floor onsite art gallery."
Eric
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4-star downtown art hotel with a 9,000-square-foot contemporary art museum
Art & Exhibitions
The hotel operates a 9,000-square-foot exhibition space for contemporary art, with installations and photographs displayed throughout the lobby, hallways, and guest room corridors. Temporary art galleries rotate exhibits regularly, offering a new experience on each visit. The hotel itself functions as a museum, allowing guests to view art while walking to their room or the restaurant.
Rooms
Guest rooms include immersive artist-designed interiors, 50-inch flat-screen cable TVs, and iPod docking stations. Rooms offer minibars, laptop safes, and bathrooms with bathrobes and hairdryers. Select rooms have floor-to-ceiling windows or balconies with views of downtown Louisville.
Wellness & Spa
The on-site spa includes a sauna, steam room, hammam, and full-body massage services. The hotel has a 24-hour fitness center with yoga classes and fitness/spa locker rooms. Spa facilities also include a steam room and a range of massage treatments.
Dining & Bar
The on-site restaurant Proof on Main serves southern cuisine and has a bourbon bar that hosts regular events with local distillers. Guests receive complimentary bourbon tastings at the bar. The bar also offers wine and champagne, and the restaurant provides breakfast service.
Location & Accessibility
The hotel sits on historic Whiskey Row within walking distance of the Louisville Slugger Museum & Factory, Muhammad Ali Center, and Kentucky Museum of Art & Craft. A free electric ZeroBus offers downtown transportation from the hotel. The property is 6 miles from Louisville International Airport and close to Museum Row.
Highlights
Art: 9,000-square-foot contemporary art museum inside the hotel
Dining: Proof on Main southern cuisine & bourbon bar with tastings
Wellness: Sauna, steam room, hammam, and full-body massage
Rooms: Immersive artist-designed interiors with floor-to-ceiling windows
Location: On historic Whiskey Row, near 3 major museums
Transport: Free electric ZeroBus for downtown travel
Pet: Pet-friendly accommodations allowed
“The hotel distinguishes itself with its commitment to contemporary art, seamlessly integrating installations and exhibitions throughout the property. Its location near historic Whiskey Row and the Muhammad Ali Center makes it ideal for exploring downtown Louisville, and the bourbon bar adds a touch of local flavor. In my opinion, the immersive artist-designed guest rooms create a stay that is both luxurious and thought-provoking.”
James DavidEditor-in-Chief at Dogfriendly-hotels
Select your room type
The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
Room Balcony
2 persons
29 m²
1 King-size bed
Air conditioning
Balcony
room details
Deluxe King Room
2 persons
31 m²
1 King-size bed
Air conditioning
Heating
room details
Corner Suite
2 persons
61 m²
1 King-size bed
Air conditioning
Bathtub
room details
Show all rooms
Rates & availability calendar
See current prices and availability for your chosen dates!
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Check-in/ Check-out
Facilities
Hotels feature amenities designed to keep both you and your pet comfortable
Facilities: Perfect
9.0/10Review score
General
No smoking on site
Wi-Fi
Parking
Safe deposit box
24-hour reception
Pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Luggage storage
Locker room
Allergy-free rooms
Lift
ATM/Cash machine
Smoke detectors
Electric vehicle charging station
Fire extinguishers
Sports & Fitness
Fitness centre
Yoga class
Guest Parking
Cookware/ Kitchen utensils
Services
Valet parking
Room service
Housekeeping
Laundry
Dry cleaning
Welcome drink
Dining
Restaurant
Bar/ Lounge area
Outdoor dining area
Business
Business centre
Meeting/ Banquet facilities
Fax/Photocopying
Children
Cots
Spa & Leisure
Spa & wellness centre
Sauna
Turkish bath
Steam room
Full body massage
Room features
Air conditioning
Heating
Mini-bar
Soundproofed rooms
Patio
Tea and coffee facilities
Ironing facilities
Bathroom
Free toiletries
Self-catering
Cookware/ Kitchen utensils
Media
Flat-screen TV
Room decor
Carpeted floor
Show more
Dining Onsite
At 21C Museum Hotel Louisville, culinary experiences await that reflect the spirit of American flavors in a modern setting. Guests can indulge in the vibrant offerings at Proof on Main, where innovative dishes and rich beverages create memorable moments, complemented by special events that celebrate regional distillers and unique spirits.
Proof on Main
American
Ambiance
A modern setting infused with artistic touches, creating an inviting and contemporary atmosphere that encourages conversation and connection.
Key Offerings
Signature dishes feature local ingredients, with special events such as the Fork & Bottle dinner series showcasing guest distillers and the annually celebrated Hog & Barrel dinner featuring Pappy Van Winkle.
Reservation
Reservations are recommended for dinner and special events.
Hours vary, typically open for dinner; specific timings may change according to events.
Location
700 West Main Street, Louisville, 40202,
Explore Louisville
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Kentucky Science Center
2 minutes walking
A family-friendly science destination featuring interactive exhibits and an IMAX theater for immersive learning.
Louisville Slugger Museum & Bat Factory
3 minutes walking
Home of baseball's iconic bat, this museum offers factory tours and unique exhibits celebrating the sport's history.
Muhammad Ali Center
4 minutes walking
A cultural and educational center honoring the life of Muhammad Ali, featuring interactive exhibits on his legacy and humanitarian work.
KFC Yum Center
9 minutes walking
This large arena hosts major concerts and sporting events, making it a hub for entertainment in Louisville.
Waterfront Park
17 minutes walking
A scenic park along the Ohio River, perfect for jogging, picnicking, or relaxing with outdoor yoga sessions.
Angel's Envy Distillery
19 minutes walking
Take a distillery tour and learn about the bourbon-making process, sampling unique spirits. Reservations recommended.
Louisville Bike Rentals
5 minutes walking
Rent a bike to explore the city and parks, with multiple trails available for different skill levels.
Spas and Wellness Centers
5-10 minutes drive
Local spas offer various wellness treatments, from massages to skincare, enhancing relaxation during your stay.
Proof On Main
1 minute walking
A farm-to-table restaurant offering locally sourced dishes in a chic, art-filled setting, ideal for casual or fine dining.
Mussel & Burger Bar Downtown
1 minute walking
Gourmet burgers and fresh mussels in a vibrant atmosphere, known for innovative pairings and craft beer selections.
Bristol Bar & Grille
2 minutes walking
Casual dining with a focus on Kentucky cuisine, offering a diverse menu and local craft beers. Great for family dinners.
Los Aztecas Mexican Restaurant
3 minutes walking
Authentic Mexican dishes with a welcoming vibe, featuring vegetarian options and vibrant décor. Perfect for a casual meal.
Fourth Street Live!
10 minutes walking
An entertainment district featuring live music, dining, and nightlife, known for weekend events and a vibrant atmosphere.
Old Forester Distilling
15 minutes walking
Experience bourbon tastings and guided tours in a historic distillery with a lively tasting room and engaging staff.
Louisville Palace
12 minutes walking
Enjoy an exquisite historic theater with stunning decor, hosting concerts, movies, and various performances throughout the year.
Comedy Caravan
10 minutes driving
A local comedy club featuring stand-up acts. Perfect for couples or groups looking for a fun night out with laughs.
Local transport and travel tips
City Centre
Louisville 23 min · 1.9 km
Airports
Louisville (SDF) 18 min · 11.9 km
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in the entire hotel for free.
Children & extra beds
Maximum capacity of extra beds in a room is 1.
Pets
Pets are allowed on request.
Year renovated:
2006
Number of floors:
4
Number of rooms:
96
Former name
21c Museum Hotel
Reviews and Ratings
Feedback about 21C Museum Hotel Louisville from previous guests about their experience.
Review score
Based on 259 verified reviews
9.2 /10
Perfect
90 %
Recommend
Breakfast
2.5/10
Cleanliness
9.3/10
Comfort
9.4/10
Facilities
9.0/10
Free WiFi
10.0/10
Location
9.5/10
Paid Wi-Fi
7.5/10
Staff
9.0/10
Value for money
8.4/10
Pros
Art museum
Comfy bed
Perfect location
Friendly staff
Cons
Thin walls
Cold receptionist
Late breakfast
Indifferent attitude
Guest reviews
based on 1899 reviews
4.5/5
based on 176 reviews
9.0/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About 21C Museum Hotel Louisville
What is the check-in and check-out policy at 21C Museum Hotel Louisville?
Check-in starts at 16:00 and check-out is by 11:00.
Is parking available at 21C Museum Hotel Louisville?
Valet parking is available at the hotel.
What type of amenities are available in the rooms at 21C Museum Hotel Louisville?
Rooms feature free Wi-Fi, a 50-inch flat-screen TV, minibar, iPod docking station, and air conditioning.
What dining options are available at 21C Museum Hotel Louisville?
The hotel features an on-site restaurant, Proof on Main, offering unique southern cuisine.
What fitness facilities does 21C Museum Hotel Louisville offer?
There is a 24-hour fitness center, a sauna, and a range of spa services available.
Are there any notable attractions near 21C Museum Hotel Louisville?
Nearby attractions include the Muhammad Ali Center (0.5 km), Louisville Slugger Museum & Factory (0.5 km), and the Kentucky Museum of Art & Craft (1 km).
How far is 21C Museum Hotel Louisville from Louisville International Airport?
The hotel is 10 km from Louisville International Airport.
What services are available for business travelers at 21C Museum Hotel Louisville?
The hotel offers a business center and 17 meeting rooms for business needs.
What kind of experiences can guests expect from the art installations at 21C Museum Hotel Louisville?
The hotel includes more than 800 m² of exhibition space showcasing contemporary art installations.